Cephalexin concentration in a dental granuloma.

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[Granuloma of the palate under a dental prosthesis].

During exploration, we observed a 2.5 cm× 2 cm lesion that adopted the exact shape of the palate, of mucosal appearance, rigid consistency and reddish colour, pedunculated on a single layer of approximately 3mm in the most anterior and medial vertex of the hard palate (Figs. 1 and 2). During the time when she used the prosthesis, the neoformation was stable and ‘‘trapped’’ between the prosthesi...

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Cephalexin: a channel hydrate.

The antibiotic cephalexin [systematic name: D-7-(2-amino-2-phenylacetamido)-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid] forms a range of isomorphic solvates, with the maximum hydration state of two water molecules formed only at high relative humidities. The water content of the structure reported here (C(16)H(17)N(3)O(4)S.1.9H(2)O) falls just short of this configurati...

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Enhanced Enzymatic Production of Cephalexin at High Substrate Concentration with in situ Product Removal by Complexation

Cephalexin (CEX) was synthesized with 7-amino-3-deacetoxycephalosporanic acid (7-ADCA) and D(–)-phenylglycine methyl ester (PGME) using immobilized penicillin G acylase from Escherichia coli. It was found that substrate concentration and in situ product could remarkably influence the ratio of synthesis to hydrolysis (S/H) and the efficiency of CEX synthesis. The optimal ratio of enzyme to subst...

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Peripheral Giant Cell Granuloma Associated With Dental Implants.

Peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion of the oral mucosa arising on the buccal or lingual attached gingiva or alveolar mucosa and the crest of the edentulous alveolar ridge and contains numerous giant cells. This case series describes 3 cases regarding the clinical and surgical management of PGCG associated with dental implants. MATERIALS AND METHODS This case serie...

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ژورنال

عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics

سال: 1992

ISSN: 1882-8272,0388-1601

DOI: 10.3999/jscpt.23.235